Sakae Homma Selected Research

ErbB Receptors (EGF Receptor)

9/2023	Upregulation of long non‑coding RNA LINC00460 in EGFR‑mutant lung cancer indicates a poor prognosis in patients treated with osimertinib.
7/2021	Quantification of BIM mRNA in circulating tumor cells of osimertinib-treated patients with EGFR mutation-positive lung cancer.
1/2020	Clinical importance of long non‑coding RNA LINC00460 expression in EGFR‑mutant lung adenocarcinoma.
7/2018	PD-L1 mRNA expression in EGFR-mutant lung adenocarcinoma.
1/2015	Usefulness of nanofluidic digital PCR arrays to quantify T790M mutation in EGFR-mutant lung adenocarcinoma.
4/2014	Clinical significance of BIM deletion polymorphism in non-small-cell lung cancer with epidermal growth factor receptor mutation.
8/2012	Clinical significance of circulating tumor cells and free DNA in non-small cell lung cancer.

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Sakae Homma Research Topics

Disease

36	Idiopathic Pulmonary Fibrosis 07/2023 - 06/2004
21	Lung Neoplasms (Lung Cancer) 03/2024 - 05/2007
17	Interstitial Lung Diseases (Interstitial Lung Disease) 03/2024 - 07/2003
11	Neoplasms (Cancer) 09/2023 - 01/2010
10	Vasculitis (Vasculitides) 08/2022 - 06/2004
10	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 01/2022 - 06/2004
8	Pneumonia (Pneumonitis) 03/2024 - 02/2008
8	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 08/2012
8	Idiopathic Interstitial Pneumonias 01/2024 - 11/2005
6	Bronchiectasis 06/2021 - 10/2013
6	Respiratory Insufficiency (Respiratory Failure) 01/2011 - 10/2003
5	Microscopic Polyangiitis 10/2023 - 10/2013
5	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/2023 - 06/2004
5	Fibrosis (Cirrhosis) 07/2021 - 10/2013
5	Thymoma (Thymic Carcinoma) 06/2020 - 02/2008
5	Hemorrhage 01/2020 - 12/2008
5	Infections 01/2019 - 01/2003
5	Fever (Fevers) 05/2009 - 09/2003
4	Adenocarcinoma of Lung 03/2024 - 01/2015
4	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2024 - 08/2006
4	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 09/2023 - 01/2010
4	Glomerulonephritis 08/2022 - 01/2009
4	Pneumothorax 06/2022 - 10/2003
4	Inflammation (Inflammations) 01/2022 - 01/2015
4	Lung Diseases (Lung Disease) 11/2020 - 01/2012
4	Emphysema 07/2019 - 10/2013
4	Chronic Obstructive Pulmonary Disease (COPD) 10/2018 - 01/2017
4	Vascular Diseases (Vascular Disease) 10/2013 - 07/2003
3	Sarcoidosis (Schaumann Disease) 08/2021 - 05/2019
3	Disease Progression 07/2021 - 01/2010
3	Acute Lung Injury 02/2019 - 05/2009
3	Hypoxia (Hypoxemia) 11/2017 - 03/2005
3	Carcinoma (Carcinomatosis) 07/2017 - 10/2016
3	Pulmonary Aspergillosis 01/2017 - 05/2007
3	Dyspnea (Shortness of Breath) 08/2013 - 05/2009
2	Systemic Vasculitis 10/2023 - 01/2009
2	Trichosporonosis 09/2023 - 11/2020
2	Neoplasm Metastasis (Metastasis) 09/2023 - 07/2017
2	Circulating Neoplastic Cells 07/2021 - 08/2012
2	COVID-19 07/2021 - 01/2021
2	Thrombosis (Thrombus) 07/2021 - 11/2017
2	Rheumatoid Arthritis 06/2021 - 05/2019
2	Systemic Scleroderma (Systemic Sclerosis) 01/2021 - 10/2010
2	Lung Injury 02/2019 - 08/2004
2	Organizing Pneumonia 01/2019 - 08/2013
2	Pulmonary Arterial Hypertension 05/2018 - 10/2010

Drug/Important Bio-Agent (IBA)

16	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 10/2023 - 06/2004
10	pirfenidoneIBA 11/2021 - 01/2013
7	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2023 - 03/2005
7	ErbB Receptors (EGF Receptor)IBA 09/2023 - 08/2012
7	nintedanibIBA 01/2023 - 01/2017
7	Peroxidase (Myeloperoxidase)IBA 08/2022 - 06/2004
7	ThrombomodulinIBA 01/2020 - 01/2015
6	Biomarkers (Surrogate Marker)IBA 11/2020 - 10/2016
6	CollagenIBA 01/2019 - 07/2003
6	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2014 - 07/2003
5	Acetylcysteine (Siran)FDA LinkGeneric 01/2021 - 04/2012
5	SteroidsIBA 08/2011 - 02/2005
4	Carboplatin (JM8)FDA LinkGeneric 03/2024 - 08/2006
4	RNA (Ribonucleic Acid)IBA 09/2023 - 11/2016
4	Phosphotransferases (Kinase)IBA 07/2023 - 01/2019
4	Proteins (Proteins, Gene)FDA Link 05/2019 - 04/2014
4	Tyrosine Kinase InhibitorsIBA 01/2019 - 08/2012
3	Carcinoembryonic AntigenIBA 03/2024 - 01/2007
3	Immune Checkpoint InhibitorsIBA 03/2024 - 12/2017
3	4- (2- fluoro- 4- ((((2- phenylacetyl)amino)thioxomethyl)amino)phenoxy)- 7- methoxy- N- methyl- 6- quinolinecarboxamideIBA 07/2023 - 01/2019
3	Oxygen (Dioxygen)IBA 06/2023 - 08/2004
3	Antifibrotic AgentsIBA 10/2021 - 02/2018
3	C-Reactive ProteinIBA 01/2021 - 06/2004
3	Immunoglobulins (Immunoglobulin)IBA 06/2020 - 06/2010
3	Gefitinib (Iressa)FDA Link 01/2020 - 01/2015
3	AntigensIBA 12/2019 - 03/2003
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2019 - 01/2014
3	Anti-Bacterial Agents (Antibiotics)IBA 06/2010 - 09/2003
2	Paclitaxel (Taxol)FDA LinkGeneric 03/2024 - 09/2023
2	Cell-Free Nucleic AcidsIBA 09/2023 - 08/2012
2	osimertinibIBA 09/2023 - 07/2021
2	Bevacizumab (Avastin)FDA Link 09/2023 - 04/2017
2	AutoantibodiesIBA 01/2022 - 10/2013
2	Messenger RNA (mRNA)IBA 07/2021 - 07/2018
2	Voriconazole (Vfend)FDA LinkGeneric 06/2021 - 06/2007
2	PeriostinIBA 05/2021 - 11/2020
2	Azithromycin (Zithromax)FDA LinkGeneric 01/2021 - 04/2009
2	polyglucosanIBA 12/2019 - 01/2017
2	Vasopressins (Vasopressin)IBA 10/2019 - 06/2007
2	Bleomycin (Blenoxane)FDA LinkGeneric 01/2019 - 12/2017
2	B7-H1 AntigenIBA 09/2018 - 07/2018
2	Prednisolone (Predate)FDA LinkGeneric 05/2018 - 09/2003
2	Bronchodilator Agents (Bronchodilators)IBA 05/2018 - 09/2003

Therapy/Procedure

39	Therapeutics 04/2022 - 12/2003
11	Drug Therapy (Chemotherapy) 01/2024 - 08/2006
6	Aftercare (After-Treatment) 04/2022 - 04/2009
5	Traction 07/2019 - 10/2013
5	Remission Induction 07/2019 - 01/2017
3	Radiotherapy 03/2024 - 02/2008
2	Humidifiers 09/2023 - 11/2020
2	Chest Tubes (Chest Tube) 06/2022 - 01/2010
2	Thymectomy 06/2020 - 02/2008
2	Thoracotomy 06/2020 - 09/2015
2	Immunotherapy 11/2019 - 12/2017